TPO and hypothyroidism: The most common screening approach reported in all the articles was a trimester specific Thyroid Stimulating Hormones (TSH) test followed by estimation of Thyroxine (free T4) and Thyroid antibody test (TPO-Ab) [47, 49, 50] and Levothyroxine was the treatment of choice with regular monitoring of TSH level for Overt hypothyroidism.