In recent years, EIF4G1 expression has been found to be significantly increased in a variety of tumours, such as breast cancer, ovarian cancer, prostate cancer, multiple myeloma and nasopharyngeal carcinoma, and EIF4G1 plays a central role in promoting tumour angiogenesis, malignant transformation and phagocytosis during tumour progression.20, 21, 22, 23, 24. Here, EIF4G1 is linked to Familial prostate cancer.