KLF5 and kidney disorder: As summarized in Table 2, increased renal expression of KLF5 was seen in other animal models of various aetiological kidney diseases, for instance, in the renal medulla of spontaneously hypertensive rats, in which the mRNA expression of renal KLF5 was increased along with the progression of renal epithelial‐mesenchymal transition71; in the kidneys of mice irradiated at the renal region with single dose of 16 Gy, in which, renal tissues were collected at the 10 and 20‐week time‐point after irradiation and showed a significant increase in KLF5 mRNA.66