To date, a single study which demonstrated that in clear cell renal cell carcinoma (ccRCC), KLF5 protein expression was lower in tumour tissues as compared to adjacent normal renal tissues and was also lower in different ccRCC (A498, RCC4 and 786‐O) cell lines compared to immortal renal HEK‐293T cells.37 This evidence concerns the gene KLF5 and nonpapillary renal cell carcinoma.