H19 and neoplasm: Studies on the expression, recruitment of chromatin trimmings, regulation of X chromosome inactivation (XIST) (Zhu et al. 2018), genomic imprinting (H19) (Luo et al. 2018), protein folding and protein activity, other processes have revealed that lncRNAs can function carcinogenic or tumor suppressor genes in tumor development (Zhang and Ho 2019).