IDH2 and neoplasm: In the case of IDH-mutant 1p/19q cases, the “entropy” and “non-uniformity” measures that both refer to the randomness in the region of interest were higher in the 1p/19q-codeleted group than in the 1p/19q-noncodeleted group, indicating that the tumors in the former group contained more regions with high gray levels, suggestive of higher radiologic heterogeneity.37 Other important features for accurate prediction of 1p/19q codeletion status were the location of the tumor, the features of the T2-weighted histogram, and other texture features.