The cytokines interleukin 6 (IL-6), interleukin 1 beta (IL-1β), tumor necrosis factor alpha (TNF-α) and chemokine C–C motif ligand 2 (CCL2), 3 (CCL3), and 5 (CCL5) are upregulated and represent potential targets for treatment of patients with COVID-19 [16]. This evidence concerns the gene TNF and COVID-19.