10 Bhargav Bhargav PRK PRK Mishra Mishra A A Agarwal Agarwal G G et et al al  Prevalence of Hypothyroidism in Benign Breast Disorders and Effect of Thyroxine Replacement on the Clinical Outcome  Prevalence of Hypothyroidism in Benign Breast Disorders and Effect of Thyroxine Replacement on the Clinical Outcome  World Journal of Surgery  World Journal of Surgery  2009  2009 33 33 2087 2087 93 93 19641955 19641955. This evidence concerns the gene PLK3 and hypothyroidism.