CD274 and polycystic ovary syndrome: Moreover, in the PCOS group and the control group, there were significant differences in the haplotypes GAAA, TAAA, GAAC, TAAC, GAGC, GCAA, TCAA, GCGA, TCGA, GCAC, and TCGC of the rs2282055, rs2890658, rs702275, and rs10125854 SNP loci of the PD-L1 gene (Table 6, P < 0.05).