A previous study shows that RCC2 overexpression promotes metastasis of Lung Adenocarcinoma (LUAD) by inducing Epithelial-Mesenchymal Transition (EMT) through modulation of mitogen-activated protein kinase-c-Jun N-terminal kinase (MAPK -JNK) signaling pathway (Pang et al., 2017). The gene discussed is RCC2; the disease is lung adenocarcinoma.