The baseline characteristics, including sex, age, ECOG-PS, HBV infection, cirrhosis, Child-Pugh class, BCLC stage, alpha-fetoprotein (AFP) level, AST level, tumor size, number of tumor nodes, extrahepatic metastasis, portal vein tumor thrombus (PVTT), history of previous surgery, and procedures of TACE, were not significantly different between the two groups (Supplementary Table 1). The gene discussed is AFP; the disease is neoplasm.