Increased concentrations of TGF-β1 in course of development of lung fibrosis induce EMT (epithelial-mesenchymal transition) of alveolar epithelial cells type II (AET II cells) (89) and EndMT (endothelial-mesenchymal transition) of microvascular endothelial cells (90). This evidence concerns the gene TGFB1 and pulmonary fibrosis.