TF and liver disorder: An abnormal glycosylation is also a known phenomenon in liver disease patients; it has been described in alcoholic liver disease (decreased enzyme activities of mannosyltransferase and galactosyltransferase, lowered intracellular dolichol concentration, desialylation of serum Tf, α1-antitrypsin and ceruloplasmin; hyperfucosylation of haptoglobin and serum Tf), galactosemia and fructosemia (the pattern resembling CDG type I), chronic hepatitis B and C, non-alcoholic steatohepatitis, and bile-related liver diseases (6–21).