TNF-α engagement of its receptors, TNF-R1 and TNF-R2, mediates cell recruitment to sites of infection, immune cell activation, and production of antimicrobial molecules, cytokines, and can result in programmed cell death (Klebanoff et al., 1986; Bekker et al., 2001; Wajant et al., 2003). This evidence concerns the gene TNF and infection.