AKT1 and liver cancer: For example, via competitively binding to miR-16-5p, lncRNA AGAP2-AS1 (AGAP2 antisense RNA 1) could weaken the inhibitory effect of miR-16-5p on annexin A11, thereby promoting the migration and invasion of liver cancer cells by enhancing the activation of AKT (protein kinase B) signal pathway (28).