GLI1 and liver cancer: Mechanistically, by directly binding to IGF2BP1 (insulin-like growth factor 2 mRNA-binding protein 1), LINC01093 could interfere with the interaction between IGF2BP1 and GLI1 (glioma-associated oncogene homolog 1) mRNA, thus leading to the degradation of GLI1 mRNA, which further affects the expression of GLI1 downstream genes involved in the development of liver cancer (15).