The diagnosis accuracy of Model ADC that referred to four lectins (DBA, STL, UEA-I, and BPL) in the training cohort was appraised by ROC analysis, indicating that Model ADC had higher discriminatory power for differentiating ADC from SCC and SCLC (AUC: 0.776, sensitivity: 0.787, and specificity: 0.729) than that of the two single candidate lectins, such as DBA (AUC: 0.634, sensitivity: 0.520, and specificity: 0.729), and PHA-E (AUC: 0.634, sensitivity: 0.720, and specificity: 0.583). This evidence concerns the gene RPS19 and small cell lung carcinoma.