PDGFRB and atrial fibrillation: Through other studies on fibroblast models of AF patients, dogs, and rats, other researchers have discovered that the PDGF-BB/PDGFR-β signaling pathway promotes the proliferation of cardiac fibroblasts and the secretion of type I collagen, which is an element in the formation of atrial fibrosis and may become a new focus for AF intervention [12].