A study among Indian adults aged 17 to 59 years suggests that patients with obesity and MS may be a subtype of asthmatics with more severe asthma (p < 0.05), worse quality of life (p < 0.05), high risk of apnea obstructive sleep (p < 0.05), and higher levels of inflammatory markers (leptin and IL-6, p < 0.05) compared to nonobese asthmatic patients and obese asthmatics without MS [47]. Here, LEP is linked to obesity due to melanocortin 4 receptor deficiency.