The authors found an increased risk of T2DM (HR = 2.12 (95% CI 1.43–3.14), p value> 0.001), and CHD (HR = 1.50 (95% CI 1.07–2.10), p value 0.02) in asthma and argue that the association with asthma-T2DM and asthma-CHD probably involves the sharing of common immunogenic and environmental conditions, such as production of inflammatory cytokines IL-6 and IL-17 already identified in all those clinical conditions and extrinsic mechanisms such as hypoxia and tachyarrhythmia present in exacerbations of asthma and capable of triggering symptoms of CHD. This evidence concerns the gene IL6 and asthma.