The univariable Cox regression analysis showed that mutation count, BMI, APF, liver cirrhosis, tumor stage, TNM stage, ECOG, and the 15-lncRNA-based classifier were related with RFS, and the multivariate Cox regression analysis further showed that mutation count, AFP, T stage, ECOG, and the 15-lncRNA-based classifier were independent predictors of RFS (Table 3). This evidence concerns the gene AFP and neoplasm.