Finally, we investigated the role of the SNHG17-miR-3180-3p-RFX1 axis in the progression of HCC using control, SNHG17, SNHG17+si-RFX1, and SNHG17+si-RFX1+miR-3180-3p inhibitor transfected Huh7 cells. Here, RFX1 is linked to hepatocellular carcinoma.