It has been directly reported to be functionally correlated with IL-13 (Higham et al., 2020; Min et al., 2020) and IL-17 (Kamijo et al., 2020; Mamber et al., 2020) in focal regions surrounding airway smooth muscles at the transcriptomics level and is further pathologically correlated with several chronic lung diseases, including chronic obstructive pulmonary diseases (Min et al., 2020). This evidence concerns the gene IL17A and chronic lung disease.