FLT3 and acute myeloid leukemia: Conversely, the transferring-conjugated anionic lipopolyplex nanoparticle synthetic miR-29b mimics Tf-NP-miR-29b was shown to downregulate DNMTs, cyclin-dependent kinase (CDK) 6, SP1, KIT, and FLT3, to suppress AML growth, to impair colony formation, and to reduce cell viability in vitro in AML patient samples (87).