We also transferred sera isolated from mice at different time points post Py infection (day 18, 32 and 72) following the rationale that, if Abs are indeed mediating an effective anti-parasite response, this effect should be even clearer at early time points of infection when the differences between anti-LAG-3 and control isotype Ab treated mice are the greatest (day 18). The gene discussed is LAG3; the disease is infection.