SIRT1 and neoplasm: Numerous reports indicate melatonin’s stimulatory effect on SIRT1 expression in different types of non-tumor cells (Shah et al., 2017; Chen et al., 2019; Savran et al., 2019; Xu et al., 2019) and tissues, including heart (Favero et al., 2020) and kidneys (Bai et al., 2016; Shi et al., 2019).