CSAG2 is more polyadenylated and translated by CPEB4 in paclitaxel-resistant ovarian cancer cells and recurrent ovarian tumors, and this post-transcriptional regulation of CSAG2 by CPEB4 has a causal link to paclitaxel resistance, because CSAG2 knockdown attenuates CPEB4-mediated paclitaxel resistance in ovarian cancer cells. The gene discussed is CPEB4; the disease is ovarian carcinoma.