CD68 and colitis: Data here obtained show tissue sections from WT mice had a basal counting of CD68+ macrophages which increased due to DSS administration, regardless of pioglitazone treatment, and indeed, corresponding areas on sections immunostained for AnxA1 evidenced there is a positive correlation between number of CD68+ macrophages and AnxA1 expression, as both increased proportionally when mice were subjected to development of DSS-induced colitis.