It is reported by authors in biopsies from Crohn’s disease patients that AnxA1 expression correlates only with myeloperoxidase-positive neutrophils excluding CD68+ macrophages in lamina propria (Reischl et al., 2020), but others report the opposite by showing AnxA1 expression correlates with increased CD68+ counting in tissue biopsies from ulcerative colitis and Crohn’s disease patients, in agreement with our findings (Vong et al., 2012). This evidence concerns the gene MPO and Crohn disease.