Growing evidence suggests IQGAP3 is overexpressed in various tumors, including melanoma, pancreatic cancer, gastric cancer, bladder cancer, hepatocellular carcinoma, and breast cancer (Yang et al., 2014; Hu et al., 2016; Xu et al., 2016; Oue et al., 2017; Shi et al., 2017). This evidence concerns the gene IQGAP3 and familial pancreatic carcinoma.