In particular, the accumulation of α-synuclein in substantia nigra, olfactory bulb, hippocampus, amygdala, prefrontal cortex, and locus coeruleus replicated non-motor features of human PD pathology such as anxiety or cognitive dysfunction (Flores-Cuadrado et al., 2016; Schapira et al., 2017; Butkovich et al., 2018; Henrich et al., 2018; Stoyka et al., 2020). The gene discussed is SNCA; the disease is Anxiety.