UBE3A and Anxiety: ASD mice models with FMR1, PTEN, UBE3A, and GABRB3 mutations exhibit learning deficits, stereotypic behaviors, and anxiety phenotypes (Jiang et al., 2010; Tanaka et al., 2012; Gandhi et al., 2014; Clipperton-Allen and Page, 2015; Zieba et al., 2019).