In the training cohort time course analyses of endothelial vulnerability markers showed that ANG2 remained stable in EB patients (no SEP) between preconditioning and day +28, whereas other endothelial markers such as CXCL8/IL8, ST2, and IL18 significantly increased in EB patients compared to non-EB patients early after alloSCT (Fig. 4). This evidence concerns the gene IL18 and epidermolysis bullosa.