Furthermore, qRT-PCR detection confirmed that the expressions of APCDD1L-AS1 and SIRT5 were lower, and the expressions of miR-1322, miR-1972 and miR-324-3p were significantly higher in Lv-shRNA-APCDD1L-AS1 tumor tissues than the Lv-NC tumor tissues (Fig. 8c-d). This evidence concerns the gene SIRT5 and neoplasm.