The expression of the CD30 antigen in PTCL tumor tissue was shown by IHC, and the results revealed that CD30-positive PTCL tissue had much more brown or light brown staining (Fig. 1A, right) than CD30-negative tissue (Fig. 1A, left). Here, TNFRSF8 is linked to mature T-cell and NK-cell non-Hodgkin lymphoma.