To test whether AMPK signaling may be involved in human KRAS/LKB1 mutant lung adenocarcinoma we performed a correlation analysis between pAMPK and oncogenic codon 12 KRAS mRNA for LKB1 loss-of-function and LKB1 wild-type patients using TCGA data. The gene discussed is STK11; the disease is lung adenocarcinoma.