Interestingly, survival analyses of another datasets with the exact characteristics but of grade III breast tumors revealed that miR-182 associates with poor prognosis when down-regulated in grade III tumors of 395 patients (Supplementary Fig. 2a) and that Cx43 associates with poor prognosis when up-regulated in 903 patients with grade III breast tumors (Supplementary Fig. 2b). Here, GJA1 is linked to breast neoplasm.