DNMT3B and colorectal neoplasm: DKO cell DNMT3B targets (from Fig. 2a) were also significantly enriched in colorectal tumour H3K36me3 marked CGIs (p < 2.2 × 10−16, Fisher’s exact test) and depleted in colorectal tumour H3K4me3 marked CGIs (p < 2.2 × 10−16, Fisher’s exact test).