PRTN3 and rheumatoid arthritis: This finding was confirmed by using the experimental classical HLA genotype dataset that demonstrated an inverse association between HLA-DQB1*03:02 allele and risk of ACPA-positive RA (OR = 0.27, 95% CI = 0.17–0.45, p = 2.30 × 10−07) (supplementary Table 6).