In detail (Table 5), dVdtmax is increased from 197.87 ± 83.18 V/s for the SR condition to 219.21 ± 90.48 V/s for the AF condition, whereas APD90 (250.10 ± 41.59 ms vs. 181.93 ± 23.66 ms) and APD50 (187.84 ± 32.36 ms vs. 121.22 ± 24.13 ms) were abbreviated due to Pitx2-induced remodelling. The gene discussed is PITX2; the disease is atrial fibrillation.