Taking advantage of our experience in the CPZ-induced cell model, some previous results showing that CPZ was able to induce cytotoxic damage mediated by a mitochondrial dysfunction in the HOG and SH-SY5Y cell lines (data not shown), and the findings reported in this work (see next figures), we aimed to analyze the potential effect of CPZ on Apo D expression in these oligodendroglioma and neuroblastoma cell lines by qRT-PCR and immunocytochemistry. Here, APOD is linked to oligodendroglioma.