NR2E3 and enhanced S-cone syndrome: Autosomal recessive NR2E3-related disease manifests as a slow disease progression in ESCS patients, with good visual acuity preservation in the vast majority of cases, good overall macular function preservation, good retention of far peripheral vision, and relatively slow progression of kinetic visual field loss as noted by previous studies [22,31,32,60,61], which is consistent with what we observed in our patients.