T2 gene mean was calculated by combining the mRNA expression levels of IL4, IL5, and IL13. T2 gene mean significantly inversely correlated with FEV1 (%) preBD (rs = −0.36, p = 0.029), and positively correlated with blood (rs = 0.42, p = 0.021) and sputum eosinophils (rs = −0.63, p < 0.001), as well as the need for biological therapy (rs = 0.53, p < 0.001) to control their asthma symptoms. The gene discussed is IL5; the disease is asthma.