Wang et al. demonstrated that NNK (4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone), one of the many tobacco carcinogens, is able to upregulate the production of the chemokine CCL20 (C-C motif chemokine ligand 20); its production was inhibited by the anti-inflammatory drug dexamethasone, thus suppressing lung cancer in vitro and in vivo [59]. The gene discussed is CCL20; the disease is lung carcinoma.