PDCD1 and neoplasm: As shown in Fig. 7C (t‐test, P <0.01) and S7C, after 12 h of coculture, the apoptosis rate of tumor cells in the PD1 OE and TOX OE groups (6.41% and 7.87%, respectively, for HSC‐3, and 7.76% and 7.83%, respectively, for CAL‐33) was significantly lower than that in the Ctrl OE group and TOX OE plus anti‐PD1 group (21.29% and 23.02%, respectively, for HSC‐3, and 16.90% and 16.98%, respectively, for CAL‐33).