Correlation analyses revealed that the expression of SLFN11 is significantly negatively correlated to five GCB-DLBCL-associated genes (MME, LRMP, MYBL1, ITPKB, BCL6), whereas it is significantly positively correlated to six ABC-DLBCL-associated genes (IRF4, PIMI, CCND2, ENTPD1, PTPN1, ETV6) (Fig 3B and 3C). Here, IRF4 is linked to diffuse large B-cell lymphoma.