TP53 and neoplasm: Indeed, candidate genes studies have found that elephant genomes encode duplicate tumor suppressors such as TP53 and LIF (Abegglen et al., 2015; Sulak et al., 2016; Vazquez et al., 2018) as well as other genes with putative tumor suppressive functions (Caulin et al., 2015; Doherty and de Magalhães, 2016).