Furthermore, while most women achieved the recommended 30 min of daily exercise, the lack of activity from 7 pm onward, usually after the largest daily carbohydrate intake, was particularly striking and accompanied by almost 20% higher overnight TAR.27 The data suggest that carefully controlled carbohydrate intake and structured daily exercise may be needed to overcome the increased peripheral insulin resistance and limit the duration of postprandial hyperglycemia during type 1 diabetes pregnancy. The gene discussed is INS; the disease is Hyperglycemia.