In the urban survey (Table 3), Sm infection was positively associated with total and SWA‐ and SEA‐specific IgE and IgG4 (p < .001), and ELISA‐determined HDM‐specific IgE (p = .037), cockroach‐specific IgE (p = .040) and cockroach‐specific IgG4 concentrations (p = .005). Here, IGHE is linked to systemic mastocytosis.