Asthma was positively associated with total IgE (1.53 [1.13, 2.05], p = .005), cockroach‐specific IgE (ELISA: 2.65 [1.31, 5.34], p = .007; ImmunoCAP®: 2.03 [1.39, 2.97], p < .001) and HDM‐specific IgE (ELISA: 4.99 [2.33, 10.72], p < .001; ImmunoCAP®: 4.79 [2.72, 8.44], p < .001) [Figure 3A]. The gene discussed is IGHE; the disease is asthma.