IGHE and asthma: Conversely, there were inverse associations between asthma and total IgE/HDM‐specific IgE ratios (0.33 [0.21, 0.50], p < .001), total IgE/cockroach‐specific IgE ratios (0.75 [0.57, 0.99], p = .047) and HDM‐specific IgG4/IgE ratios (0.24 [0.12, 0.48], p < 0.001) [Figure 3B].