ACE2 and viral infectious disease: Viral infection studies in various ACE2 expressing cell types across species (human, bats, civet, pigs, mice), computational modelling and cryo-EM experiments demonstrated unambiguously that ACE2 is the receptor for SARS-CoV-2, similar to that for other coronaviruses including SARS-CoV and middle east respiratory syndrome coronavirus (MERS-CoV) [171].