CD4 and hepatocellular carcinoma: We employed TIMER to explore the association of AKT1 expression and TIICs in HCC, and the results in Figure 10 showed that AKT1 was positively correlated with B cell (r = 0.208, P = 1.05E − 4), CD8+ T cell (r = 0.102, P = 5.93E − 2), CD4+ T cell (r = 0.467, P = 5.34E − 20), macrophage (r = 0.285, P = 8.35E − 8), neutrophil (r = 0.312, P = 3.36E − 9), and dendritic cell (r = 0.261, P = 1.09E − 6).