Follistatin-like 1 (FSTL1), for instance, a member of this family, is a BMP4 antagonist that can improve heart function after MI (Altekoester and Harvey, 2015) and abrogates aldosterone-induced cardiac myocyte hypertrophy (Tanaka et al., 2016). Here, FSTL1 is linked to myocardial infarction.