Additionally, ALKBH5 enhances the stability of the BCL-2 transcript (which increased in the epithelial ovarian cancer as well) and enhances the interaction between BCL-2 and Beclin1 that inhibit the autophagy from the other side, suggesting that the ALKBH5 controls tumor progression and autophagy flux via BCL-2 demethylation (Zhu et al., 2019). This evidence concerns the gene BCL2 and neoplasm.