FTO m6A-mediated demethylation of 3'- untranslated region BNIP3 transcript, which is a proapoptotic protein belonging to the Bcl-2 tumor suppressor family, promoting its degradation via YTHDF2 independent pathways and specific upregulation of BNIP3 retards breast cancer proliferation and metastasis (Niu et al., 2019). The gene discussed is FTO; the disease is breast carcinoma.