FTO m6A-mediated demethylation of 3'- untranslated region BNIP3 transcript, which is a proapoptotic protein belonging to the Bcl-2 tumor suppressor family, promoting its degradation via YTHDF2 independent pathways and specific upregulation of BNIP3 retards breast cancer proliferation and metastasis (Niu et al., 2019). This evidence concerns the gene BCL2 and neoplasm.