ALKBH5 and brain cancer: Additionally, ALKBH5 was found to be linked with the devastating malignant brain tumor glioblastoma through the ALKBH5-FOXM1-mediated pathway; in this milieu, ALKBH5 enhances glioblastoma tumorigenesis (Dixit et al., 2017; Zhang et al., 2017; Malacrida et al., 2020).