Similar to the OS tumorigenesis, ALKBH5 possesses a negative regulatory impact in gastric cancer (GC) via acting on another lncRNA named nuclear paraspeckle assembly transcript one that results in enhancement of EZH2 expression (a component of the polycomb repressive complex) and ultimately affects the invasion and metastasis in GC tissues (Zhang J. et al., 2019; Zhu et al., 2020). This evidence concerns the gene ALKBH5 and gastric cancer.