For example, lncTCF7 was reported to regulate TCF7 expression by recruiting SWI/SNF complex and to activate Wnt signaling pathway in maintaining self‐renewal of liver cancer stem cells.[38] In female esophageal carcinoma, exosomal FMRA‐AS1 facilitates maintenance of cancer stem‐like cells dynamic equilibrium via TLR7/NF‐κB/c‐Myc signaling.[39] LncRNA‐Hh boosts BCSC generation through the hedgehog signal pathway.[40] However, the effects of lncRNAs on CSCs, especially BCSCs remain largely unknown. Here, TLR7 is linked to liver cancer.